HISTOPATHOLOGICAL STUDIES ON HUMAN LEPROSY

Clinico Histopathological Correlation in Leprosy

Introduction: Leprosy is a chronic, infectious disease caused by Mycobacterium leprae. It is classified into five groups based on clinical, histological, microbiological and immunological criteria (Ridley & Jopling Classification). However a great variation is seen in interpretation of clinical and histopathological examination of these lesions. The present research was taken to study the corre...

Histopathological Studies on Radiation Pneumonitis.

Studies on radiation pneumonitis have been made from the beginning of the 20th century in Europe and America. Prior to the Second World War, many articles have appeared including the works of Engelstad5> and Warren et al.25) who described the general aspects of this problem. In Japan, the incidence of this disease has been rare. A case report by Hamaguchi and Akazaki9) was only available before...

Studies on the therapy of leprosy.

Of a score or more experimental treatments employed in human leprosy at Carville only two, chaulmoogra oil and the sulfone drugs, have proved worthy of more than passing consideration. Chaulmoogra oil, of course. had been an established treatment in leprosy long before its use in this country. It was considered experimental only in the sense that it had not had an extensive and critical clinica...

Studies on Sulfone Resistance in Leprosy

Almost to be expected, as the concomitant of a new chemotherapeutic agent, is the development of drug resistance by formerly sensitive organisms. Sometimes this is such a frequen t occurrence that the drug ceases to be useful ; with other drugs the appearance of resistant strains is a rarity. Throughout the twenty year experience with sulfones in leprosy, the incidence of resistance has appeare...

Studies on Plasma Protein. IV. Leprosy